Araştırmacılar depresyonun “sirkadiyen” adlı bir alt türünü tanımladı

University of Sydney researchers have identified a distinct form of depression, which they call circadian depression, tied to the internal clock that governs the 24-hour sleep-wake cycle. Publishing in the British Journal of Psychiatry, the team analysed clinical and genetic information on over 10,000 people with depression enrolled in the Australian Genetics of Depression Study, a project focused on severe, recurrent or persistent cases. Almost a quarter, 2,604 participants, fitted the new subtype, marked by seasonal symptoms, sleeping longer during low periods, feeling exhausted on waking and a preference for late nights. They tended to fall ill younger and to have more severe symptoms. Common serotonin-based drugs such as SSRIs appear to work less well for them and to cause more side effects. Because the condition is linked to the body clock, co-senior author Jacob Crouse says treatments aimed at it, like light therapy and melatonin, may be far more relevant and should be tried much earlier.